THE ROLES OF EMOTION REGULATION AND PEER CONTEXT IN CHILDRENS ACHIEVEMENT
H Nancy
Arizona State University-tempe Campuscity: Tempe country: United States (us)
Grant 1R01HD068522-01A1 from Eunice Kennedy Shriver National Institute Of Child Health & Human Development
Abstract: The goal of this multimethod, multireporter, prospective study is to determine if, when, and why students´ positive and negative emotions are concurrently and prospectively related to their relationship with their teacher, social competence, problem behaviors, classroom engagement, and subsequent learning and achievement. A fuller understanding of these relations is critical because the knowledge can be used in prevention and intervention programs to precisely target aspects of socioemotional competence that likely positively impact learning and achievement. The first aim is to document the concurrent and prospective relations between children´s positive and negative emotions and their achievement. The second aim is to investigate the potential moderating influences of students´ own self-regulatory skills and their peers´ emotionality and self-regulation on the relations between students´ emotion and academic achievement. Aim three is designed to identify processes that might mediate the relations between children´s emotions and their achievement, including students´ relationships with their teachers and their adjustment and their motivation versus avoidance towards, and engagement in, classroom activities. Observations of various emotions in two contexts (classroom and peer) will allow for the consideration of varying mediating pathways based on the type of emotion and where it is expressed. The aims will be examined in the context of a three-year longitudinal study. Three hundred children will be followed from Kindergarten to 2nd grade. Each year, parents and teachers will report on students´ positive and negative emotions, self-regulation, relationships with teachers, social competence, problem behaviors, and engagement. Teachers will report on peers´ emotionality, self-regulation, and students´ achievement. Children will participate in tasks that assess their positive and negative emotions, their regulation, and their academic achievement. Students´ emotions will be observed while they interact with peers during recesses and during class time, while their engagement will be observed throughout the school day. Multivariate, longitudinal analyses will be used to examine prospective direct, mediated, and moderated relations. Many students are unable to perform basic reading and mathematics tasks and nearly 15% of young adults do not have a high school degree. Academic difficulties are linked to negative outcomes such as poor health, job instability, and low lifetime earning. A better understanding of students´ positive and negative emotions will aid in the dissemination of programs that can bolster academic success and ameliorate negative outcomes
Keywords: Academic achievement; Achievement; Adoption; Age; Anger; Anxiety; Arousal; base; Characteristics; Child; Competence; Data; Depressed mood; design; Educational aspects; elementary school; emotion regulation; Emotional; Emotions; Employment; experience; Fostering; Future; Goals; Health; heuristics; high school; Informal Social Control; Institute of Medicine (U.S.); interest; Intervention; intervention program; kindergarten; Knowledge; Learning; Link; Longitudinal Studies; Mathematics; Measures; Mediating; Mediation; Mediator of activation protein; Mental Health; Methods; Modeling; Motivation; National Institute of Child Health and Human Development; Occupations; Outcome; Parents; Pathway interactions; peer; peer victimization; physical conditioning; Play; positive emotional state; Prevention; Prevention program; Preventive Intervention; Problem behavior; Process; programs; prospective; Prospective Studies; psychosocial; Qualifying; Reading; Regulation; Reporter; Reporting; Research; Role; Schools; skills; social skills; statistics; Students; success; teacher; Testing; Time; young adult
Relevance: Many students are unable to perform basic reading and mathematics tasks and nearly 15% of young adults do not have a high school degree. Academic difficulties are linked to negative outcomes such as poor health, job instability, and low lifetime earning. A better understanding of students´ positive and negative emotions will aid in the dissemination of programs that can bolster academic success and ameliorate negative outcomes
Project start date: 2012-03-01
Project end date: 2017-02-28
Budget start date: 1-MAR-2012
Budget end date: 28-FEB-2013
1R01HD068522-01A1 (2012): $404581
Sponsored Links Excellgen http://Excellgen.com
Grants awarded to H Nancy
H Nancy, John Rodman Paul Professor/ Dir.grad.stu
Yale Universitycity: New Haven country: United States (us)
Grant 5R21HL098711-02 from National Heart, Lung, And Blood Institute
Abstract: The long term goal of this R21 project is to develop tools for imaging lymphatic vessels (LVs) in living mice. Lymphatic vessels drain interstitial fluid by means of valve-like openings, they transport lipids and they participate in the immune system. They transport antigen and antigen presenting cells to lymph nodes and cells from the lymph node to the circulation. When lymphatic vessels are disrupted, lymphedema, the accumulation of lymph in the interstitial tissues, occurs. Immunological functions are thwarted. Lymphangiogenesis occurs in inflammation at the site of immunization and in lymph nodes (secondary lymphoid organs) where there is an interaction between LVs and high endothelial venules (HEVs). Lymphangiogenesis occurs in chronic inflammation in lymphoid accumulations in ectopic sites, called tertiary lymphoid tissues (TLOs) that have many characteristics of lymph nodes. Mice transgenic for the rat insulin promoter (RIP) driving lymphotoxin-1 (RIPLT1) exhibit such TLOs in the pancreas. Techniques that have been used to develop mice whose HEVs can be imaged via green fluorescent protein will be used here to develop mice whose LVs can be similarly imaged via a red fluorescent protein. To attain this goal, the following specific aims will be accomplished 1. To develop transgenic mice whose lymphatic vessels express fluorescent proteins. The pCLASPER recombineering technology will be used to isolate LV genes (prox1, lyve-1, or podoplanin), insert red fluorescent reporter genes, such as tdTomato, and produce transgenic mice. 2. To evaluate lymphatic reporter transgenic mice for fidelity of expression. Mice transgenic for lymphatic vessel reporter constructs will be analyzed for co- expression of endogenous LV genes and transgenes in several tissues in the steady state, in lymph nodes after immunization, and in TLOs in RIPLT1 mice. 3. To evaluate LVs in living mice. Multiphoton in vivo microscopy will be used to evaluate fluorescent LVs. Interactions between (green) high endothelial venules and (red) lymphatic vessels in the lymph nodes of immunized mice will be analyzed in real time. A dynamic understanding of lymphangiogenesis and LV function will provide therapeutic insight into lymphatic function and dysfunction in lymphedema. The development of imaging tools for lymphatic vessels will provide insight into how LVs and HEVs are regulated, maintained, and cooperate during an immune response and provide insight into lymphangiogenesis in inflammation, transplantation, autoimmunity, infectious diseases, and cancer. A thorough understanding of lymphangiogenesis and lymphatic vessel function will provide therapeutic insight into lymphatic function and dysfunction in conditions such as lymphedema. Imaging tools for lymphatic vessels will provide insight into how this vascular system is maintained and regulated during an immune response and provide insight into lymphangiogenesis in inflammation, transplantation, autoimmunity, infectious diseases, and cancer. )
Keywords: Abbreviations; accessory cell; Antigen-Presenting Cells; Antigens; APC; ATGN; Autoimmune Status; Autoimmunity; Automobile Driving; Blood Circulation; Bloodstream; body system, allergic/immunologic; Body Tissues; Cachectin; Cachectin-Tumor Necrosis Factor; Cancers; CD44 Adhesion Receptor; CD44 Antigens; CD44 molecule; Cells; Characteristics; Chronic; Chylothorax; Circulation; Common Rat Strains; Communicable Diseases; Development; DIF; drFP583; driving; Drivings, Automobile; ds red protein; dsFP593; Dysfunction; EC 2.8.2; Endothelial Cells; Exhibits; fluid; FP593; Functional disorder; Galactosidase; Gastrointestinal Tract, Pancreas; gene product; Generalized Growth; Genes; Genes, LacZ; GFP; Goals; gp85; Greater sac of peritoneum; Green Fluorescent Proteins; Growth; Hermes Antigen; High Endothelial Venule; Homeo Boxes; Homeobox; host response; Humulin R; HUTCH-1; Hyaluronan-Binding Protein; Hyaluronic Acid Binding Protein; Image; imaging; Imaging Device; Imaging Tool; Immune response; Immune system; Immunization; immunogen; Immunologic Accessory Cells; Immunologic Stimulation; Immunological Stimulation; immunoresponse; Immunostimulation; in vivo; Infectious Disease Pathway; Infectious Diseases; Infectious Diseases and Manifestations; Infectious Disorder; Inflammation; INFLM; injured; insight; Insulin; Insulin (ox), 8A-L-threonine-10A-L-isoleucine-30B-L-threonine-; Insulin, Regular; Intercellular Fluid; interstitial; Interstitial Fluids; LacZ; LacZ Genes; Life; Lipid Trafficking; lipid transport; liquid; Liquid substance; LTA; Lymph; lymph cell; lymph gland; Lymph node proper; lymph nodes; Lymphangiogeneses; Lymphangiogenesis; Lymphatic; lymphatic fluid; Lymphatic Tissue; Lymphatic vessel; Lymphedema; Lymphocyte; Lymphocytic; Lymphoid; Lymphoid Tissue; Lymphotoxin; Lymphotoxin A; Lymphotoxin-alpha; Magnetic Resonance Imaging; Magnetic Resonance Imaging Scan; malignancy; Malignant Neoplasms; Malignant Tumor; Mammals, Mice; Mammals, Rats; MECA-79 antigen; Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance; Methods and Techniques; Methods, Other; Mice; Microscopy; Monocytes / Macrophages / APC; MR Imaging; MR Tomography; MRI; Murine; Mus; Nasal; neoplasm/cancer; NMR Imaging; NMR Tomography; Nose; Nose, Nasal Passages; Novolin R; Nuclear Magnetic Resonance Imaging; ontogeny; Organ; organ system, allergic/immunologic; Pancreas; Pancreatic; pathophysiology; periodate-lysine-paraformaldehyde; Peripheral; peripheral lymph node addressin; Peritoneal Cavity; Physiopathology; PLPF; PNAd; podoplanin; Process; Promoter; Promoters (Genetics); Promotor; Promotor (Genetics); Proteins; public health relevance; Rat; Rattus; Receptors, Hyaluronan; red fluorescent protein; Regulation; Reporter; Reporter Genes; residence; Respiratory System, Nose, Nasal Passages; Reticuloendothelial System, Lymph; Reticuloendothelial System, Lymph Node; self recognition (immune); Sensitization, Immunologic; Sensitization, Immunological; Site; Staining method; Stainings; Stains; sulfotransferase; Techniques; Technology; Temperature; theories; Therapeutic; Time; Tissue Growth; Tissues; TNF; TNF (unspecified); TNF A; TNF gene; TNF Receptor Ligands; TNF Superfamily, Member 1; TNF-alpha; TNF-b; TNF-beta; TNFSF1; TNFSF2; Transgenes; Transgenic Mice; transplant; Transplantation; Tumor Necrosis Factor; tumor necrosis factor (unspecified); Tumor Necrosis Factor Family Protein; Tumor Necrosis Factor Gene; Tumor Necrosis Factor-alpha; Tumor Necrosis Factor-Beta; Tumor Necrosis Factors; Vascular System; Zeugmatography
Relevance: A thorough understanding of lymphangiogenesis and lymphatic vessel function will provide therapeutic insight into lymphatic function and dysfunction in conditions such as lymphedema. Imaging tools for lymphatic vessels will provide insight into how this vascular system is maintained and regulated during an immune response and provide insight into lymphangiogenesis in inflammation, transplantation, autoimmunity, infectious diseases, and cancer. )
Project start date: 2010-01-15
Project end date: 2011-12-31
Budget start date: 1-JAN-2011
Budget end date: 31-DEC-2011
PFA/PA: PA-06-181
5R21HL098711-02 (2011): $206875