Margie E Lachman
Brandeis University
Project start date: 2000-04-01
Project end date: 2013-01-31
Sponsored Links Excellgen http://Excellgen.com
CONTROL BELIEFS, MEMORY, AND AGING
Margie E Lachman, Professor And Chair
Brandeis University, 415 South St, Ms #116, Waltham, Ma 02454-9110
Grant 5R01AG017920-08 from National Institute On Aging
Abstract: Many middle-aged and older adults believe as they age that memory declines are inevitable and there is little that can be done. Such beliefs of low self-efficacy and limited control over memory aging are associated with poorer performance on a wide range of memory tasks, especially among older adults. The objective of this research program is to learn more about how low control beliefs operate as a risk factor for poor memory by considering the psychological and physiological pathways whereby control beliefs and performance are related. This will be accomplished by using short-term longitudinal designs to examine strategy use, anxiety, stress reactivity and arousal as mediators. Episodic and working memory along with memory control beliefs will be assessed in adults ages 25 to 85. Participants will be drawn from a representative sample of the Greater Boston area and tested in their homes. For Aim 1, we will extend past work to consider multiple indicators of anxiety, including self-reports and neuroendocrine (cortisol) and autonomic (heart rate) system responses of stress and arousal, which can have a short- term impact and long-term damage on cognitive and physical well-being. We also will examine memory- related stress in relation to age and the use of adaptive compensatory memory strategies. It is predicted that a sense of control over memory protects older adults from disruptive anxiety and rumination and promotes persistence in the face of challenging memory tasks. There is increasing evidence that variability in functioning is associated with important aging-related outcomes. For Aim 2, we will extend work on individual differences in the sense of control to examine short-term intraindividual variability in control beliefs in relation to age and intraindividual variability in stress and memory. Short-term fluctuations in control may reflect vulnerability rather than resilience in the face of memory challenges. Variability in control is expected to be positively associated with age and stress and inversely related to memory performance. In Aim 3 we expand the focus on age differences in intraindividual changes to the everyday context using a daily diary approach. It is expected that on days when adults feel more in control of their lives they will use more adaptive memory aids and strategies, experience less stress, and have fewer memory problems. Memory problems in later life can lead to anxiety and distress, but there are things that can be done to compensate. A focus on beliefs about controllability, the role of anxiety, and use of compensatory strategies for memory declines provides a useful framework for advancing our understanding of adaptive beliefs and behaviors for successful aging. Narrative Good memory functioning is critical in everyday life (e.g., taking medications, remembering appointments) to maintain health, well-being, and independence. This research can identify modifiable beliefs and behaviors that are tied to poor memory and reduced functioning in instrumental activities for daily living. The results can be used to develop more effective interventions to reduce distress, impairment and dependence, enhance control beliefs and memory, and improve everyday functioning in later life
Keywords: 21+ years old; Adult; Aeroseb-HC; Affective; Age; Age Reporting; Aged 65 and Over; Aging; Analysis, Data; Anxiety; Appointment; Area; Area Under Curve; Arousal; Artifacts; Autonomic nervous system; Behavior; Behavioral; Belief; Boston; Cardiovascular; Cardiovascular Body System; Cardiovascular system; Cardiovascular system (all sites); Cell Communication and Signaling; Cell Signaling; Cetacort; Chronotropism, Cardiac; Chronotropisms, Cardiac; City of Boston; Cognition; Cognitive; Compensation; Computer Programs; Computer software; Cort-Dome; Cortef; Cortenema; Cortisol; Cortispray; Cortril; Coupled; Data; Data Analyses; Dependence; Depression; Dermacort; Detection; Development; Diaries; Diaries (PT); Diaries [Publication Type]; Distraction; Distress; Drugs; ECG; EKG; Education; Educational Achievement; Educational Status; Educational aspects; Eldecort; Elderly; Elderly, over 65; Electrocardiogram; Electrocardiography; Expectancy; Eye; Eyeball; Face; Financial compensation; Finding of distraction; Goals; Grant; HPA; Head and Neck, Saliva; Health; Heart Rate; Home; Home environment; Human, Adult; Hydrocortisone; Hydrocortone; Hytone; IADL; Impairment; Individual Differences; Intervention; Intervention Strategies; Intracellular Communication and Signaling; Lead; Learning; Length of Life; Life; Link; Living Wills; Longevity; Maintenance; Maintenances; Measures; Mediator; Mediator of Activation; Mediator of activation protein; Medication; Memory; Memory, Immediate; Memory, Short-Term; Memory, Shortterm; Mental Depression; Method LOINC Axis 6; Methodology; Methods; Modeling; Models, Theoretic; Morphologic artifacts; Mortality; Mortality Vital Statistics; Nature; Neuroendocrine; Neuroendocrine System; Neurosecretory Systems; Nutracort; Organ System, Cardiovascular; Outcome; Participant; Pathway interactions; Patient Self-Report; Pattern; Pb element; Performance; Personal Satisfaction; Persons; Pharmaceutic Preparations; Pharmaceutical Preparations; Physiologic; Physiological; Pilot Projects; Play; Pregn-4-ene-3, 20-dione, 11, 17, 21-trihydroxy-, (11beta)-; Prevention; Principal Investigator; Procedures; Process; Proctocort; Programs (PT); Programs [Publication Type]; Psychological Factors; Psychology, Physiologic; Psychology, Physiological; Psychophysiological; Psychophysiology; Recovery; Relative; Relative (related person); Reporting; Research; Risk; Risk Factors; Role; Saliva; Sampling; Self Efficacy; Self-Report; Senescence; Short-Term Memory; Signal Transduction; Signal Transduction Systems; Signaling; Software; Specific qualifier value; Specified; Stress; Suggestion; System; System, LOINC Axis 4; Testing; Theoretical model; Therapeutic Hydrocortisone; Thinking; Thinking, function; Time; Variant; Variation; Vascular, Heart; Vendor; Work; adult human (21+); adult youth; advanced age; age dependent; age difference; age effect; age related; aging effect; base; biological adaptation to stress; biological signal transduction; circulatory system; cognitive function; computer program/software; diaries; distraction; drug/agent; educational level; effective intervention; elders; experience; facial; functional outcomes; geriatric; heart rate variability; heavy metal Pb; heavy metal lead; hypothalamic-pituitary-adrenal (HPA) axis; hypothalamic-pituitary-adrenal axis; hypothalmus-pituitary-adrenal axis; improved; indexing; instrumental activity of daily living; interest; interventional strategy; late life; later life; life span; lifespan; longitudinal design; methods to study multiple-level influences; mid life; mid-life; middle age; middle aged; midlife; multilevel analysis; multilevel model; multilevel modeling; older adult; older person; pathway; physical conditioning; pilot study; programs; protective behavior; psycho-physiological; psychologic; psychological; reaction; crisis; remediation; resilience; response; senescent; senior citizen; social; social role; stress response; stress; reaction; theories; training achievement; training level; training status; well-being; working memory; young adult
Project start date: 2000-04-01
Project end date: 2013-01-31
Budget start date: 15-MAR-2010
Budget end date: 31-JAN-2011
PFA/PA: PA-07-070
5R01AG017920-08 (2010): $288595
5R01AG017920-05 (2004): $232500
5R01AG017920-04 (2003): $232500
5R01AG017920-03 (2002): $271250
5R01AG017920-02 (2001): $232500
Grants awarded to Margie E Lachman
MIDLIFE COGNITION: BIOPSYCHOSOCIAL MECHANISM
Margie E Lachman
University Of Wisconsin Madison
suite 6401
madison, Wi 537151218
Grant 1P01AG020166-01A10003 from National Institute On Aging IRG: ZAG1
Abstract: The maintenanceof effectivecognitivefunctioningacross the lifespan is a crucial componentof an individual´s well-beingandability to function independentlyin society.Althoughthere isa large literatureon cognitive performancein cider adulthood,there is limited nformation about cognitivefunctioning inmidlife. The proposed research will address that need by characterizing cognition across midlife and into old age on key domains that are hypothesizedto be sensitive to age effects, including verbal memory, working memory, executive function, reasoning,and speed of processing. Cognitive testing will be carried out through telephone interviews as part of the MIDUS II study. This will create a unique opportunity to examine the performance of middle-aged adults in a large-scale, nationally representative sample. In addition, the MIDUS study will provide a rich data base that will enable us to examine the relationship betweencognitive performance and a variety of biopsychosocial factors. The goal is to identify antecedents of effective cognitive function, in order to determine those factors that may serve a protective role in maintaining mental abilities, as well as those factors that serve as risk factors for exacerbating cognitive declines. We will investigate the links between cognitive performance and variables of interest, including SES, health, control beliefs, stressful life events, and menopausal status. Specifically, we predict that cumulative advantage (including high SES, good physical and mental health status, adaptive health behaviors, low stress, and a strong sense of mastery and control) will serve as a protective buffer against age decrements in cognitive performance in midlife and later life. Conversely, we expect that cumulative adversity (including low SES, chronic poor health, limited psychosocial resources) will be associated with greater vulnerability for cognitive deficits. We also will examine whether changes associated with the menopause are related to cognitive aging. A final goal is to carry out longitudinal analyses with an oversample from the Boston area, tested in 1996 on a multi-factor cognitive battery, stress reactivity measures, and control beliefs. This will provide valuable information on how changes over time in stress and psychosocial variables impact changes in cognitive performance during midlife. Understandingthe pathways to adaptive cognitive functioning in midlife may contribute to early detection and possible prevention of aging-related cognitive decline
Keywords: cognition, human middle age (35-64), psychobiology, psychological aspect of aging, social psychology functional ability, health, health behavior, human old age (65+), locus of control, longitudinal human study, memory, menopause, mental health epidemiology, performance, psychological stressor, short term memory, socioeconomics behavioral /social science research tag, clinical research, human subject, interview, psychological test, telecommunication
Project start date: 2003-01-01
Project end date: 2008-12-31
CONTROL BELIEFS, MEMORY, AND AGING
Margie E Lachman, Professor And Chair
Brandeis University, 415 South St, Ms #116, Waltham, Ma 02454-9110
Grant 3R01AG017920-07S1 from National Institute On Aging
Abstract: Many middle-aged and older adults believe as they age that memory declines are inevitable and there is little that can be done. Such beliefs of low self-efficacy and limited control over memory aging are associated with poorer performance on a wide range of memory tasks, especially among older adults. The objective of this research program is to learn more about how low control beliefs operate as a risk factor for poor memory by considering the psychological and physiological pathways whereby control beliefs and performance are related. This will be accomplished by using short-term longitudinal designs to examine strategy use, anxiety, stress reactivity and arousal as mediators. Episodic and working memory along with memory control beliefs will be assessed in adults ages 25 to 85. Participants will be drawn from a representative sample of the Greater Boston area and tested in their homes. For Aim 1, we will extend past work to consider multiple indicators of anxiety, including self-reports and neuroendocrine (cortisol) and autonomic (heart rate) system responses of stress and arousal, which can have a short- term impact and long-term damage on cognitive and physical well-being. We also will examine memory- related stress in relation to age and the use of adaptive compensatory memory strategies. It is predicted that a sense of control over memory protects older adults from disruptive anxiety and rumination and promotes persistence in the face of challenging memory tasks. There is increasing evidence that variability in functioning is associated with important aging-related outcomes. For Aim 2, we will extend work on individual differences in the sense of control to examine short-term intraindividual variability in control beliefs in relation to age and intraindividual variability in stress and memory. Short-term fluctuations in control may reflect vulnerability rather than resilience in the face of memory challenges. Variability in control is expected to be positively associated with age and stress and inversely related to memory performance. In Aim 3 we expand the focus on age differences in intraindividual changes to the everyday context using a daily diary approach. It is expected that on days when adults feel more in control of their lives they will use more adaptive memory aids and strategies, experience less stress, and have fewer memory problems. Memory problems in later life can lead to anxiety and distress, but there are things that can be done to compensate. A focus on beliefs about controllability, the role of anxiety, and use of compensatory strategies for memory declines provides a useful framework for advancing our understanding of adaptive beliefs and behaviors for successful aging. Narrative Good memory functioning is critical in everyday life (e.g., taking medications, remembering appointments) to maintain health, well-being, and independence. This research can identify modifiable beliefs and behaviors that are tied to poor memory and reduced functioning in instrumental activities for daily living. The results can be used to develop more effective interventions to reduce distress, impairment and dependence, enhance control beliefs and memory, and improve everyday functioning in later life
Keywords: 21+ years old; Adult; Aeroseb-HC; Affective; Age; Age Reporting; Aged 65 and Over; Aging; Analysis, Data; Anxiety; Appointment; Area; Area Under Curve; Arousal; Artifacts; Autonomic nervous system; Behavior; Behavioral; Belief; Boston; Cardiovascular; Cardiovascular Body System; Cardiovascular system; Cardiovascular system (all sites); Cell Communication and Signaling; Cell Signaling; Cetacort; Chronotropism, Cardiac; Chronotropisms, Cardiac; City of Boston; Cognition; Cognitive; Compensation; Computer Programs; Computer software; Cort-Dome; Cortef; Cortenema; Cortisol; Cortispray; Cortril; Coupled; Data; Data Analyses; Dependence; Dermacort; Detection; Development; Diaries; Diaries (PT); Diaries [Publication Type]; Distraction; Distress; Drugs; ECG; EKG; Education; Educational Achievement; Educational Status; Educational aspects; Eldecort; Elderly; Elderly, over 65; Electrocardiogram; Electrocardiography; Expectancy; Eye; Eyeball; Face; Factors, Psychological; Financial compensation; Finding of distraction; Goals; Grant; HPA; Head and Neck, Saliva; Health; Heart Rate; Home; Home environment; Human, Adult; Hydrocortisone; Hydrocortone; Hytone; IADL; Impairment; Individual Differences; Intervention; Intervention Strategies; Intracellular Communication and Signaling; Lead; Learning; Length of Life; Life; Link; Living Wills; Longevity; Maintenance; Maintenances; Measures; Mediator; Mediator of Activation; Mediator of activation protein; Medication; Memory; Memory, Immediate; Memory, Short-Term; Memory, Shortterm; Method LOINC Axis 6; Methodology; Methods; Modeling; Models, Theoretic; Morphologic artifacts; Mortality; Mortality Vital Statistics; Nature; Neuroendocrine; Neuroendocrine System; Neurosecretory Systems; Nutracort; Organ System, Cardiovascular; Outcome; Participant; Pathway interactions; Patient Self-Report; Pattern; Pb element; Performance; Personal Satisfaction; Persons; Pharmaceutic Preparations; Pharmaceutical Preparations; Physiologic; Physiological; Pilot Projects; Play; Pregn-4-ene-3, 20-dione, 11, 17, 21-trihydroxy-, (11beta)-; Prevention; Principal Investigator; Procedures; Process; Proctocort; Programs (PT); Programs [Publication Type]; Psychological Factors; Psychology, Physiologic; Psychology, Physiological; Psychophysiological; Psychophysiology; Recovery; Relative; Relative (related person); Reporting; Research; Risk; Risk Factors; Role; Saliva; Sampling; Self Efficacy; Self-Report; Senescence; Short-Term Memory; Signal Transduction; Signal Transduction Systems; Signaling; Software; Specific qualifier value; Specified; Stress; Suggestion; System; System, LOINC Axis 4; Testing; Theoretical model; Therapeutic Hydrocortisone; Thinking; Thinking, function; Time; Variant; Variation; Vascular, Heart; Vendor; Work; adult human (21+); adult youth; advanced age; age dependent; age difference; age effect; age related; aging effect; base; biological adaptation to stress; biological signal transduction; circulatory system; cognitive function; computer program/software; depression; diaries; distraction; drug/agent; educational level; effective intervention; elders; experience; facial; functional outcomes; geriatric; heart rate variability; heavy metal Pb; heavy metal lead; hypothalamic-pituitary-adrenal (HPA) axis; hypothalamic-pituitary-adrenal axis; hypothalmus-pituitary-adrenal axis; improved; indexing; instrumental activity of daily living; interest; interventional strategy; late life; later life; life span; lifespan; longitudinal design; methods to study multiple-level influences; mid life; mid-life; middle age; middle aged; midlife; multilevel analysis; multilevel model; multilevel modeling; older adult; older person; pathway; physical conditioning; pilot study; programs; protective behavior; psycho-physiological; psychologic; psychological; reaction; crisis; remediation; resilience; response; senescent; senior citizen; social; social role; stress response; stress; reaction; theories; training achievement; training level; training status; well-being; working memory; young adult
Project start date: 2009-08-05
Project end date: 2010-10-31
Budget start date: 5-AUG-2009
Budget end date: 31-OCT-2010
PFA/PA: PA-07-070
3R01AG017920-07S1 (2009): $16773
1R01AG017920-01 (2000): $230575
MIDLIFE COGNITION: BIOPSYCHOSOCIAL MECHANISM
Margie E Lachman
University Of Wisconsin Madison Suite 6401 Madison, Wi 537151218
Grant 5P01AG020166-060003 from National Institute On Aging IRG: ZAG1
Keywords: cognition
STRATEGIES TO PROMOTE ADAPTIVE SELF-CONCEPTIONS FOR ENHANCED PHYSICAL ACTIVITY
Margie E Lachman
Institution:
Grant 7P50AG011669-040001 from National Institute On Aging
Keywords: body physical activity, cognitive behavior therapy, human old age (65+), injury prevention, self concept, accidental fall, belief, exercise, fear, handicapped, health behavior, health education, memory, psychological adaptation, training, human subject, interview, questionnaire, videotape /videodisc