Protein Production
293FT, 293E, CHO

Truly Functional Protein
95% Purity
1-10 mg in 2 weeks

GeneExpressoMax™
293Expresso™

Transfection Reagents
* 90% Efficiency
* 95% Viability
* No sera interference
* Simple protocol
* High-throughput
* Only $98/ml

Baculovirus
Functional Protein
95% Purity
Fast turnaround
1-10 mg from Sf9 cells

Adenovirus, AAV
& Lentivirus

ORF or shRNA
* High Titer
* Cre, FLP, ΦC31
* Protein Kinases
* Transcription Factors
* Luciferases, GFP, RFP
* Protein Production
* Stable Cell Line


Excellgen

PATERNAL INVOLVEMENT IN CHILDHOOD ASTHMA

Friedman Deborah
Massachusetts General Hospitalcity: Boston    country: United States (us)

Grant 5R03HD055322-02 from Eunice Kennedy Shriver National Institute Of Child Health & Human Development

Abstract: Asthma is a significant public health problem affecting many children and considerable coordination within the family is required to manage asthma effectively. Research identifying family factors that contribute to successful management is crucial to the development of effective interventions to reduce asthma morbidity. Research on family asthma management has focused primarily on the mother-child dyad, and little is known about parental coordination of asthma care in two-parent families. How parents work together as a team in sharing asthma management tasks, the amount of parental conflict around asthma care, as well as the degree of congruence in maternal and paternal approaches to asthma management may significantly impact the child´s health. The primary objective of this project is to investigate the associations between inter-parental processes surrounding asthma care and child asthma outcomes. Three key predictor variables will be examined 1) Parental conflict around asthma management, 2) Parental congruence, or the degree to which parents hold similar beliefs about asthma medication and have similar approaches to asthma management, and 3) Parental collaboration, or the degree to which parents work together and support each other in the care of their child´s asthma. Two main outcomes, adherence to daily preventive medications and asthma control, will be investigated. Participants will include 110 two-parent families with a child between the ages of 5 and 9 years who has persistent asthma. The child´s actual controller medication use will be electronically monitored for a period of 1 month, and families will then participate in an interview based assessment on family processes and asthma management. Parent report will provide information on asthma control. It is proposed that parental collaboration will positively impact child health outcomes, while parental incongruence (i.e. mother and father have different beliefs or approaches) and parental conflict will have a high degree of negative impact on asthma outcomes. Results of the proposed study will provide the foundation for future family based interventions to enhance adaptive family system involvement in pediatric asthma management

Keywords: 0-11 years old; Address; Adherence; Adherence (attribute); Affect; Age; Allergens; Asthma; Asthma in Children; base; Behavior; Belief; Bronchial Asthma; Caring; Child; Child Care; Child Development; Child health care; Child Youth; Childhood Asthma; children; Children (0-21); Collaborations; Complex; Conflict; Conflict (Psychology); Demographic Factors; Development; Diagnosis; drug/agent; Drugs; effective intervention; Emotional; Family; Family Process; Fathers; Foundations; Future; Gender; Health, Child; Hour; Human, Child; Infant and Child Development; Intervention; Intervention Strategies; interventional strategy; Interview; Medication; medication adherence; medication compliance; Medicine; Monitor; Morbidity; Morbidity - disease rate; Mothers; Outcome; Parents; Participant; Pediatric asthma; Pharmaceutic Preparations; Pharmaceutical Preparations; Play; Preventive; Process; Public Health; public health medicine (field); Puericulture; Regimen; Reporting; Research; Role; satisfaction; Science of Medicine; social role; Symptoms; System; System, LOINC Axis 4; Work; youngster

Relevance: Asthma is a significant public health problem, and considerable coordination within the family is required to manage asthma effectively. Little is known, however, about parental coordination of asthma care in two-parent families. Results of the proposed study will provide the foundation for future family-based interventions that include both parents to enhance adaptive management of pediatric asthma

Project start date: 2009-02-01

Project end date: 2012-01-31

Budget start date: 1-FEB-2010

Budget end date: 31-JAN-2012

PFA/PA: PA-06-180

5R03HD055322-02 (2010): $87615


Sponsored Links Excellgen http://Excellgen.com

Transient Protein Expression in CHO and HEK293 Cells
Transient Expression, Truly Functional Protein, 95% purity, 1~20 mg, fast turnaround. $5500, $3950
Recombinant Lentivirus & Adenovirus
High Yield and High Titer up to 1010 (lentivirus) and 1013 (adenovirus) for Guaranteed Expression of GOI. $3000, $2500
Baculovirus Protein Expression
Fast turn around, >95% purity functional protein. No outsourcing to China or India. $5500, $3950