Cynthia L Battle
Butler Hospital (providence, Ri)
Project start date: 2010-04-01
Project end date: 2013-01-31
Sponsored Links Excellgen http://Excellgen.com
Grants awarded to Cynthia L Battle
Family Treatment For Postpartum Depression
Cynthia L Battle, Assistant Professor
Butler Hospital (providence, Ri) 345 Blackstone Blvd Providence, Ri 02906
Grant 5K23MH066402-04 from National Institute Of Mental Health IRG: ZMH1
Abstract: This Mentored Patient-Oriented Research Career Development Award (K23) application is to support Dr. Battle s development as an independent research scientist with expertise in developing and evaluating psychosocial treatments for depressed childbearing women. Her emphasis will be on creating a comprehensive intervention that promotes positive outcomes not only for the depressed mother, but also for other family members, in particular the children who are at risk for developmental problems. This area of research is important in light of the limited psychosocial treatment options currently available for depressed childbearing women, and the long-term negative consequences for children of depressed mothers. Dr. Battle s initial goal is to develop a family treatment for postpartum depression based on an existing, well-established model of family assessments and treatment, the McMaster Model of Family Functioning. Dr. Battle s training goals are to 1) gain experience with treatment development, particularly family approaches to treating depression, 2) develop expertise treating and conducting research with depressed postpartum women, 3) improve skills in research design, methodology and ethics relevant to intervention research, 4) learn assessment techniques needed for evaluating child and maternal-child outcomes, 5) develop advanced statistical techniques relevant to clinical trials research, and 6) improve manuscript preparation and grant-writing skills. This training plan will be accomplished through 1) the resources available at Brown University Medical School; 2) high quality mentorship provided by Dr. Ivan Miller, Dr. Michael O-Hara, Dr. Ronald Seifer, and Dr. Teri Pearlstein; 3) completion of formal coursework, seminars and supervised clinical experiences; and 4) implementation of the proposed research project. As part of the career development award, Dr. Battle will complete a 5-year research plan focused on developing and evaluating the efficacy of the McMaster Family treatment for Postpartum Depression (MFTP). After an initial period of treatment development (Year 1), a randomized controlled pilot trial will be conducted between years 2-4, the findings from which will be used to further refine the treatment during a revision phase in year 5. Results from this research will be sued to justify an R01 application for a full-scale clinical trial to evaluate the efficacy of MFTP, which will be submitted during the final year of the award. This larger investigation will include more substantive assessment of child and family outcomes, building on the specialized training that Dr. Battle receives during the course of the K23 award.
Keywords: family structure /dynamics, family therapy, human therapy evaluation, major depression, method development, postpartum, psychotherapy, clinical trial, emotional adjustment, mother child interaction, outcomes research, psychological stressor, social psychology, women s health, behavioral /social science research tag, clinical research, human subject, patient oriented research
Project start date: 2002-09-23
Project end date: 2007-06-30
5K23MH066402-04 (2005): $177500
5K23MH066402-03 (2004): $177592
1K23MH066402-01 (2002): $177137
5K23MH066402-05 (2006): $177424
Treatment-Seeking For Depression Among Pregnant Women
Cynthia L Battle, Assistant Professor
Butler Hospital (providence, Ri)
345 Blackstone Blvd
providence, Ri 02906
Grant 5R34MH079108-02 from National Institute Of Mental Health IRG: SRNS
Abstract: Major depression affects over 600,000 pregnant women annually and has been consistently linked with numerous adverse consequences for mothers and developing infants, including higher rates of spontaneous abortion, preeclampsia, operative delivery, and postpartum depression. Although promising interventions have been developed to treat the disorder, treatment-seeking rates remain alarmingly low, particularly among pregnant women from low-income and racial/ethnic minority backgrounds. A critical need exists to find ways to increase appropriate treatment-seeking in depressed pregnant women, particularly those from poor and minority backgrounds. Prior to developing interventions or implementing system changes that attempt to increase treatment seeking rates, we must first understand the barriers that exist to treatment utilization. Given the lack of any published research in this area, researchers currently know little about these barriers, or how these barriers may differentially affect pregnant women from underserved groups. We propose an exploratory mixed methods study that will be the first empirical investigation of barriers to depression treatment during pregnancy, with a particular focus on identifying issues of most relevance to certain underserved patient groups. Specifically, this investigation will target low-income depressed Latina and non-Latina White patients at an obstetrical clinic serving financially disadvantaged women. We will integrate quantitative and qualitative methods to explore women´s attitudes regarding depression treatment-seeking, and to clarify processes by which symptoms are recognized and treatment decisions are made. Our research will address three primary aims (1) To identify specific factors and barriers that lead low-income, depressed pregnant women to pursue depression treatment, or to not pursue treatment; (2) To evaluate the acceptability of specific treatments for antenatal depression; (3) To develop a preliminary model of the processes by which depressed pregnant women interpret symptoms and choose whether or not to seek treatment. On a more exploratory basis, we will examine whether or not differences are observed between Latina and non-Latina White women with regard to each of the primary aims. Depression during pregnancy is associated with numerous adverse consequences for mothers and their developing infants; however, the majority of depressed pregnant women do not receive any treatment. This study will examine the reasons why some pregnant women seek help for their depression, and others do not. Results will help provide the basis for better, more acceptable, and accessible services for this vulnerable group of women
Keywords: depression, health behavior, low socioeconomic status, mental health service, pregnancy, racial /ethnic difference, women`s health Hispanic American, caucasian American, decision making, health care service availability, health care service evaluation, health disparity, medically underserved population, mental disorder diagnosis, model design /development, psychological model behavioral /social science research tag, clinical research, female, health services research tag, human subject, interview
Project start date: 2007-08-13
Project end date: 2010-06-30
5R34MH079108-02 (2008): $198903
1R34MH079108-01A1 (2007): $196376
DEVELOPMENT OF A HOME-BASED FAMILY TREATMENT FOR POSTPARTUM DEPRESSION
Cynthia L Battle, Assistant Professor (research)
Butler Hospital (providence, Ri), 345 Blackstone Blvd, Providence, Ri 02906
Grant 5R34MH083065-02 from National Institute Of Mental Health
Abstract: Although 10-15% of women experience postpartum depression (PPD) after giving birth to a child, the majority do not receive any form of mental health treatment. As highlighted in NIMH PA-06-376 "Women´s Mental Health in Pregnancy and the Postpartum Period," developing a wider range of treatment options for women with PPD is critically important given the serious repercussions associated with the disorder for both the mother and the developing infant. Very few empirically-supported treatments exist for women with PPD, and the depression treatments most widely available in the community involve psychopharmacology, an approach viewed to be unacceptable by many postpartum women, particularly those who are breastfeeding. Family-based interventions are particularly well-suited to treat PPD, in that postpartum depression occurs during a period of significant family transition; moreover, research has shown that poor family functioning and low levels of partner support predict the onset and course of the disorder. Given the serious repercussions of PPD, the lack of existing treatments, and the critical role of the family in the disorder, we propose to develop and evaluate a novel family-based treatment, Family Treatment for Postpartum Depression (FTP) which will target specific areas of family dysfunction associated with PPD. The PI has already completed an open pilot trial of an initial, clinic-based version of FTP, finding that it was acceptable to patients, feasible to administer, and possibly efficacious. In this application, we propose to expand the intervention and evaluate it in a pilot randomized controlled trial, comparing it to a supportive individual therapy condition. In recognition of the many barriers that can contribute to low utilization rates of postpartum women, particularly those who are breastfeeding, treatment will be optionally provided in the home, for patients who find this more convenient, rather than requiring women to travel to a clinic setting for care. In addition, strategies will be taken to broaden the generalizability of the treatment to a wider range of patient groups. Following an initial period of treatment refinement, we propose to conduct a pilot randomized controlled pilot trial to evaluate the feasibility, acceptability and preliminary efficacy of the intervention, comparing the family treatment to supportive psychotherapy. In addition, we will develop and evaluate a therapist-training program. Findings from the small RCT will be used to provide the basis for an R01 grant application to support a full-scale randomized treatment outcome study. Postpartum depression (PPD) is associated with numerous adverse consequences for mothers and their developing infants; however, the majority of women with PPD do not receive any treatment. This study will focus on developing a novel, home-based family treatment for PPD and will evaluate this intervention in a pilot randomized controlled trial. This approach is intended to provide a more acceptable and accessible type of treatment for postpartum women who may otherwise not seek traditional, clinic-based mental health care
Keywords: 0-11 years old; Address; Applications Grants; Appointment; Area; Behavior Conditioning Therapy; Behavior Modification; Behavior Therapy; Behavior Treatment; Behavior or Life Style Modifications; Behavioral; Behavioral Conditioning Therapy; Behavioral Modification; Behavioral Therapy; Behavioral Treatment; Birth; Breast Feeding; Breastfeeding; Care, Health; Caring; Child; Child Youth; Children (0-21); Clinic; Cognitive deficits; Communities; Conditioning Therapy; Controlled Clinical Trials, Randomized; Data; Depression, Postpartum; Development; Disadvantaged; Disease; Disorder; Dysfunction; Emotional Depression; Ethnic and Racial Minorities; Family; Functional disorder; Future; Gestation; Grant Proposals; Grants, Applications; Healthcare; Home; Home environment; Human, Child; Impairment; Individual; Infant; Intervention; Intervention Strategies; Investigation; Life Style Modification; Mental Health; Mental Hygiene; Minority Groups; Mothers; NIH; NIMH; National Institute of Mental Health; National Institute of Mental Health (U.S.); National Institutes of Health; National Institutes of Health (U.S.); Outcome; Outcome Study; Parturition; Patients; Pharmacology-Psychopharmacology; Physiopathology; Post-Natal Depression; Post-Partum Depression; Postnatal Depression; Postpartum; Postpartum Depression; Postpartum Period; Postpartum Women; Pregnancy; Psychological Health; Psychopharmacology; Psychopharmacology / Toxicology; Psychotherapy; Public Health; Randomized; Randomized Controlled Clinical Trials; Randomized Controlled Trials; Research; Role; Self Efficacy; Study, Outcome; Symptoms of depression; Training Programs; Travel; Treatment Efficacy; Treatment Period; Treatment outcome; United States National Institute of Mental Health; United States National Institutes of Health; Vulnerable Populations; Woman; Women, Postpartum; base; behavior intervention; behavioral intervention; children; depressed mother; depression; depressive; depressive symptoms; design; designing; disease/disorder; experience; innovate; innovation; innovative; intervention design; intervention development; interventional strategy; maternal depression; novel; pathophysiology; pilot trial; psychologic; psychological; psychosocial; public health medicine (field); randomisation; randomization; randomized controlled study; randomized trial; randomly assigned; social role; socioeconomic; socioeconomically; socioeconomics; therapeutic efficacy; therapeutically effective; therapy design; therapy development; treatment days; treatment design; treatment development; treatment duration; trial comparing; youngster
Project start date: 2008-07-01
Project end date: 2011-04-30
Budget start date: 1-MAY-2009
Budget end date: 30-APR-2010
PFA/PA: PAR-06-248
5R34MH083065-02 (2009): $202054