Johns Hopkins Short Term Training Grant In Infectious And Tropical Diseases In Pe
Robert H Gilman, Professor
International Healthjohns Hopkins University
Grant 5T35AI065385-03 from National Institute Of Allergy And Infectious Diseases, IRG: MID
Abstract: Despite the toll that infectious diseases take on humans in developing countries around the world, there remains a substantial shortage of both clinically and research-oriented people trained in tropical disease diagnosis, prevention, and control. Renewal of this proposed T35 training grant would enable Johns Hopkins University to continue providing U.S. medical students, candidates for graduate school and post-doctoral trainees opportunities in tropical disease research. Furthermore, funding will allow us to continue taking advantage of the substantial overseas site research-training infrastructure built over the last 20 years in Peru. We have successfully used this system to train over 205 students -171 both on an ad hoc basis and with the assistance of other grants, and 34 under the resources of this training grant. We propose to expand our program to train 30 additional students for periods of 6 months or longer. This research would continue to be performed as an independent study project and is an ideal mechanism for recruiting outstanding students into combined clinical and laboratory based research in tropical infectious diseases that can be translated to the field setting. Similar to the tutor system used in Britain, our students are each paired with an experienced investigator for the duration of their stay. Students consult with tutors frequently through all steps of the investigative process. After a 4 to 6 week lab rotation, students formulate their individual research questions. Students carry out complete scientific investigations from the initial and ongoing ethical considerations, to finally, the data analysis. After analyzing the findings of their project, or if time constraints dictate, data from another project, each student will write and submit a paper for publication
Project start date: 2006-09-01
Project end date: 2011-08-31
Sponsored Links Lab Supply Mall http://www.labsupplymall.com
Johns Hopkins Short Term Training Grant In Infectious And Tropical Diseases In Pe
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 5T35AI065385-02 from National Institute Of Allergy And Infectious Diseases, IRG: MID
Abstract: Despite the toll that infectious diseases take on humans in developing countries around the world, there remains a substantial shortage of both clinically and research-oriented people trained in tropical disease diagnosis, prevention, and control. Renewal of this proposed T35 training grant would enable Johns Hopkins University to continue providing U.S. medical students, candidates for graduate school and post-doctoral trainees opportunities in tropical disease research. Furthermore, funding will allow us to continue taking advantage of the substantial overseas site research-training infrastructure built over the last 20 years in Peru. We have successfully used this system to train over 205 students -171 both on an ad hoc basis and with the assistance of other grants, and 34 under the resources of this training grant. We propose to expand our program to train 30 additional students for periods of 6 months or longer. This research would continue to be performed as an independent study project and is an ideal mechanism for recruiting outstanding students into combined clinical and laboratory based research in tropical infectious diseases that can be translated to the field setting. Similar to the tutor system used in Britain, our students are each paired with an experienced investigator for the duration of their stay. Students consult with tutors frequently through all steps of the investigative process. After a 4 to 6 week lab rotation, students formulate their individual research questions. Students carry out complete scientific investigations from the initial and ongoing ethical considerations, to finally, the data analysis. After analyzing the findings of their project, or if time constraints dictate, data from another project, each student will write and submit a paper for publication
Project start date: 2006-09-01
Project end date: 2011-08-31
5T35AI065385-02 (2007): $67769
Grants awarded to Robert H Gilman
NEW AND EMERGING GASTROINTESTINAL PATHOGENS
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 5U01AI035894-05 from National Institute Of Allergy And Infectious Diseases, IRG: SRC
Abstract: This project examines the role of emerging gastrointestinal pathogens in Peru, a developing country. Newer viral agents appear to be important causes of childhood diarrhea. Cyclospora cayetanensis, a coccidial parasite recently identified by our group, is an important cause of disease in children, travelers and AIDS patients. Cysticercosis is an important cause of late onset epilepsy and other neurological conditions. The epidemiology or viral diarrhea in our shanty town population will be defined using recently developed diagnostic tools for detection of new viral agents including astro, enteric adeno, calci, norwalk and toro viruses. The importance of secondary rotavirus infection will be determined. Cyclospora cayetanensis, is a protozoa recently identified by our group and named after the Peruvian university, Cayetano Heredia. Its epidemiological role in children´s diarrhea, and its seroprevalence will be described in a Peruvian shanty town. The antigenic and molecular structure of Cyclospora cayetanensis will be further defined. Children infected with this parasite will be randomized for treatment in a double blind trial to determine if trimethoprim/sulfamethoxazole is an effective therapy. New immunological tools for diagnosing cysticercosis will be developed and then tested in Peru, a highly endemic zone. Pigs, an intermediate host of cysticercosis, will be used as sentinels to predict changes in environmental infection with Taenia solium eggs
Keywords: Peru, cooperative study, diarrhea, epidemiology, helminthiasis human subject
Project start date: 1994-08-01
Project end date: 1999-04-30
5U01AI035894-05 (1998): $463944
5U01AI035894-04 (1997): $495310
1U01AI035894-01 (1994): $436467
Screening And Risk Factors For Cogenital Chagas Disease In Bolivia
Robert H Gilman, Professor
International Healthjohns Hopkins University
Grant 5R21AI072093-02 from National Institute Of Allergy And Infectious Diseases, IRG: CRFS
Abstract: Ten percent or more of mothers with chronic Trypanosoma cruzi infection give birth to infected infants, many of whom will develop life-threatening sequelae of Chagas disease at birth, shortly after birth or later in life. Until recently, congenital Chagas disease has been neglected as a public health problem. Now that regional Chagas disease control programs have begun to dramatically reduce the incidence of vector-borne and transfusion-associated transmission, maternal-to-infant transmission is the most frequent route in many endemic areas. There are 10-12 million persons living with chronic T. cruzi infection in Latin America; hundreds of thousands of Latin American immigrants to the United States and other industrialized countries are infected as well. Perhaps a third of these are women and girls under the age of 45 years who can transmit the parasite to their offspring during sequential pregnancies because infection is lifelong. Recent studies have demonstrated that treatment of congenitally infected infants with antitrypanosomal drugs shortly after birth is highly effective. However, cure is increasingly difficult to achieve as the child grows older. The Pan American Health Organization recommends diagnosis and treatment of all infants with congenital Chagas disease, but technical, logistical, and economical obstacles have prevented any country from implementing a nationwide congenital Chagas disease intervention program. In the majority of infected infants, congenital Chagas disease is subclinical or presents with subtle nonspecific findings. Therefore, the most promising approach to congenital Chagas disease is universal laboratory-based screening of infants for T. cruzi infection. At present, there is no sufficiently sensitive and logistically feasible diagnostic test for congenital Chagas disease in the first days of life. The goal of this application is develop a sensitive and specific diagnostic assay for congenital Chagas disease that could be used for mass screening of newborns. We will also study the epidemiology of congenital Chagas disease in Santa Cruz, Bolivia and identify maternal and infant risk factors for congenital transmission of T. cruzi, in order to develop strategies for efficient targeting and implementation of screening programs, and to provide the basis for developing other novel approaches to decrease the prevalence and adverse sequelae
Keywords: trypanosomiasis Carnivora, Trypanosoma cruzi, aging, base, birth, children, diagnosis, diagnostic test, disease /disorder prevention /control, epidemiology, genetics, health, immigrant, infection, mass screening, parent, pregnancy, pregnancy infection, public health clinical research
Project start date: 2007-07-15
Project end date: 2009-06-30
1R21AI072093-01 (2007): $212522
INTERGRATED CONTROL OF TAENIA SOLIUM CYSTICERCOSIS
Robert H Gilman, Professor
Johns Hopkins University W400 Wyman Park Building Baltimore, Md 212182680
Grant 3U01AI035894-10S1 from National Institute Of Allergy And Infectious Diseases, IRG: ZAI1
Abstract: Taenia solium cysticerosis is increasingly recognized as an important public health hazard in both disease-endemic regions of the developing world and in areas with high immigrant populations in developing countries. T. solium has been recognized as a potentially eradicable parasite by WHO. However, no control strategy has been demonstrated to be effective and sustainable, excepting the improvement in public health that accompanies general development. Four independent yet closely related components will provide information required to shortcut development for porcine cysticerosis, and better understanding of the natural history of the disease, specifically in 3) T. solium transmission dynamics and 4) human Cysticerosis clinical evolution.
Keywords: Cestoda, Peru, cooperative study, epidemiology, helminthiasis, parasitic gastrointestinal disorder
Project start date: 1999-09-01
Project end date: 2006-07-31
3U01AI035894-10S1 (2004): $28750
3U01AI035894-10S2 (2004): $890159
5U01AI035894-10 (2003): $955217
5U01AI035894-08 (2001): $617406
5U01AI035894-07 (2000): $621508
INTEGRATED CONTROL OF TAENIA SOLIUM CYSTICERCOSIS
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 2U01AI035894-06 from National Institute Of Allergy And Infectious Diseases, IRG: ZAI1
Abstract: Taenia solium cysticerosis is increasingly recognized as an important public health hazard in both disease-endemic regions of the developing world and in areas with high immigrant populations in developing countries. T. solium has been recognized as a potentially eradicable parasite by WHO. However, no control strategy has been demonstrated to be effective and sustainable, excepting the improvement in public health that accompanies general development. Four independent yet closely related components will provide information required to shortcut development for porcine cysticerosis, and better understanding of the natural history of the disease, specifically in 3) T. solium transmission dynamics and 4) human Cysticerosis clinical evolution
Keywords: Cestoda, Peru, cooperative study, epidemiology, helminthiasis, parasitic gastrointestinal disorder
Project start date: 1999-09-01
Project end date: 2004-08-31
2U01AI035894-06 (1999): $616528
Significance Of Edema Around Calcified Brain Cysticerci
Robert H Gilman, Professor
Johns Hopkins University W400 Wyman Park Building Baltimore, Md 212182680
Grant 5R03TW005562-03 from Fogarty International Center, IRG: ICP
Abstract: Neurocysticercosis is a major cause of acquired epilepsy in most developing countries, accounting for their higher prevalence rates of epilepsy. Intraparenchymal brain cysts may resolve by natural evolution or following antiparasitic therapy with either praziquantel or albendazole, leaving in most cases a calcified scar. Many, if not most, patients with NCC will present with symptoms years after the viable infection resolved, but show only calcified lesions on brain CT. However, the long-term consequences of the residual calcified scars have not yet been evaluated despite recent evidence linking neurological symptoms (specifically seizures) to perilesional edema around calcifications. This study will test the hypothesis that new symptoms in patients with calcified cysticercosis, especifically seizures, are associated with the presence of edema around at least one calcified lesion. A prospective, nested case-control study will be performed designed to evaluate the relation of perilesional edema around calcified brain cysticerci and the recurrence of neurological symptoms (specifically seizures). Over 60 patients have already been recruited and 36 more were identified from a cohort of 120 patients with parenchymal, neurocysticercosis who participated in an FDA-funded double blind, randomized study to determine the benefit of albendazole treatment versus placebo. Patients with newly diagnosed calcified neurocysticercosis will be also added into the study cohort to increase sample size. Cases are defined as cohort patients who present a seizure event after at least three months without symptoms. Controls are cohort patients who have had no neurological symptoms in the last three months. Twelve strata defined on age and number of lesions are defined. At the time of appearance of new seizures, the affected individual will be evaluated by MRI together with an asymptomatic control from the same stratum. This design excludes the effects of age and numbers of lesions. The proportion of patients with perilesional edema will be compared between cases and controls to determine the existence and strength of the association.
Keywords: brain edema, calcification, epilepsy, onchocerciasis, prognosis, brain disorder diagnosis, diagnosis design /evaluation, longitudinal human study, nervous system disorder epidemiology, nervous system disorder therapy, vaccine development, clinical research, computed axial tomography, diagnostic test, electroencephalography, human subject, magnetic resonance imaging
Project start date: 2002-07-15
Project end date: 2005-06-30
5R03TW005562-03 (2004): $32847
5R03TW005562-02 (2003): $34132
SEROLOGY AS A PREDICTOR OF NEUROCYSTICERCOSIS
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 5R03TW000598-03 from Fogarty International Center, IRG: ICP
Abstract: Neurocysticercosis (NCC) is a major cause of acquired epilepsy in most developing countries and has been diagnosed with increasing frequency in the United States. The disease is caused by the larval stage of the tapeworm Taenia solium. Albendazole is the most effective therapy available for intraparenchymal cysts, resolving all lesions in about 50% of patients. This amended application seeks to correlate serological markers with treatment effectiveness in a cohort of Peruvian patients with parenchymal NCC treated with albendazole. Serological monitoring using an advanced immunoblot assay will characterize the evolution of the anti-parasite response in terms of antigen specificity and immunoglobulin isotype. Serological, clinical, and radiographic data will then be compared in a blind fashion to determine the relation between changes in antigen-specific immunoglobulin isotypes and therapy effectiveness
Keywords: Cestoda, anthelmintic, diagnosis design /evaluation, helminthiasis, human therapy evaluation, parasitic disease chemotherapy, parasitic disease diagnosis, serology /serodiagnosis antibody formation, epilepsy clinical research, computed axial tomography, human subject, western blotting
Project start date: 1997-09-30
Project end date: 2000-07-31
5R03TW000598-03 (1999): $23250
5R03TW000598-02 (1998): $23063
Infectious Diseases Training Program In Peru
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 5D43TW006581-05 from Fogarty International Center, IRG: ZRG1
Abstract: Infectious Disease Research Training Program in Peru. Background. Over the past 15 years we have developed a research network in Peru that combines state-of-the-art research with high-quality training. This collaboration between UPCH, A.B.PRISMA, international trainers and JHU mentors people as they progress from trainee to independent scientist and in turn themselves become trainers. Over the past 10 years, this NIH funded network has trained 94 Peruvians, 37 of whom have been funded to study at US universities. Importantly, all of the MSc and PhDs remain based in Peru. This strengthening of Peruvian research expertise has also been achieved by training 158 visitors from other countries, three of who have consequently moved to Peru, where they now lead research and training. Over 10 years this has resulted in over 150 trainee publications directly related to this research. Proposed training principles This grant would allow our training network to further expand, building upon its internationally recognized strengths whilst increasing accessibility for candidates from disadvantaged regions and introducing a curriculum of core subjects taught in regular seminars. Specifically, we would continue to maximize trainee growth through . One-to-one mentorship from local, visiting and returning experts . Achievement-driven stepwise progression for those with greatest ability . Respect for equality of opportunity irrespective of gender and ethnicity. Proposed training structure This network will continue to be broad-based (numbers are for 5 years) 1. Mentorship in Peru will remain the foundation of this program. Bright candidates will be selected for one-to-one mentorship from a trainer within the apprenticeship setting of a research project (approximately 100). 2. Peru formal training will constitute laboratory, rotations and one-week long training seminars (approximately 250). 3. Peru MSc training for the most able candidates selected by their mentor and trainers (10). 4. USA diploma (10), MPH (1) and PhD (2) training at JHU will be provided for the highest achievers who are judged to have potential to become independent scientists and trainers. This grant will facilitate the growth and enhancement of this effective and egalitarian training network, allowing physicians and scientists to both benefit from and contribute to the sustainable development of infectious disease research in Peru and other countries
Keywords: Peru, communicable disease, health science research support, training international cooperation, mentoring /mentor human subject
Project start date: 2003-09-05
Project end date: 2009-03-31
5D43TW006581-05 (2007): $181945
1D43TW006581-01 (2003): $149992
3D43TW006581-04S1 (2006): $196633
5D43TW006581-04 (2006): $142493
3D43TW006581-03S1 (2005): $159255
5D43TW006581-03 (2005): $149965
3D43TW006581-02S1 (2004): $81680
5D43TW006581-02 (2004): $149042
FIELD-APPLICABLE SEROLOGIC DIAGNOSIS AND EXPERIMENTAL CONTROL STRATEGIES
Robert H Gilman
Institution:
Grant 5U01AI035894-030003 from National Institute Of Allergy And Infectious Diseases, IRG:
Abstract: Human Taenia solium cysticercosis is a severely debilitating, yet treatable disease. In the pig, this infection accounts for multimillion dollars of economic loss per year. Preliminary epidemiological surveys with the newly developed immmunoblot assay (EITB) in many Latin American countries, China, and India indicated that this is a significant public health problem with prevalence rates ranging from 8% to 15% in humans and up to 45% in pigs. A recent Centers for Disease Control Survey showed endogenous transmission in families with immigrant domestic workers, resulting in a sero- prevalence of 13% in a single community in Brooklyn alone. Cysticercosis has therefore, acquired a domestic mode. Control of this important public health problem is dependent on the identification and treatment of patient and pigs. We propose to extend and enhance the power, usefulness, and practicality of our unique assay/field operation system toward the detection and control of this important disease. We also propose to test the efficacy of a novel pig/human approach to surveillance and control of cysticercosis. We will 1. To develop a low cost, robust, and field applicable version of the EITB assay for the detection of human and pig cysticercosis 2, determine the longevity of infection-specific antibodies in treated patients by quantitative isotype assays 3, To test the hypothesis that a single treatment of EITB positive pigs, together with elimination of tape worms in sero-positive human patients, and eduction is a viable and effective approach to the control of human and pig cysticercosis 4, to determine if the serology of cysticercosis-free pigs is a useful and effective sentinel for measuring disease prevalence and control effectiveness of human cysticercosis.
Keywords: Peru, diagnosis design /evaluation, epidemiology, helminthiasis, parasitic disease diagnosis, serology /serodiagnosis, Cestoda, anthelmintic, clinical trial, communicable disease control, cooperative study, diagnostic test, disease reservoir, health education, human therapy evaluation, humoral immunity, immunoglobulin G, immunoglobulin isotype, nonhuman therapy evaluation, parasitic disease chemotherapy, feces analysis, field study, human subject, swine, western blotting
Johns Hopkins Short Term Training Grant In Infectious And Tropical Diseases In Pe
Robert H Gilman, Professor
International Healthjohns Hopkins University
Grant 5T35AI065385-03 from National Institute Of Allergy And Infectious Diseases, IRG: MID
Abstract: Despite the toll that infectious diseases take on humans in developing countries around the world, there remains a substantial shortage of both clinically and research-oriented people trained in tropical disease diagnosis, prevention, and control. Renewal of this proposed T35 training grant would enable Johns Hopkins University to continue providing U.S. medical students, candidates for graduate school and post-doctoral trainees opportunities in tropical disease research. Furthermore, funding will allow us to continue taking advantage of the substantial overseas site research-training infrastructure built over the last 20 years in Peru. We have successfully used this system to train over 205 students -171 both on an ad hoc basis and with the assistance of other grants, and 34 under the resources of this training grant. We propose to expand our program to train 30 additional students for periods of 6 months or longer. This research would continue to be performed as an independent study project and is an ideal mechanism for recruiting outstanding students into combined clinical and laboratory based research in tropical infectious diseases that can be translated to the field setting. Similar to the tutor system used in Britain, our students are each paired with an experienced investigator for the duration of their stay. Students consult with tutors frequently through all steps of the investigative process. After a 4 to 6 week lab rotation, students formulate their individual research questions. Students carry out complete scientific investigations from the initial and ongoing ethical considerations, to finally, the data analysis. After analyzing the findings of their project, or if time constraints dictate, data from another project, each student will write and submit a paper for publication
Project start date: 2006-09-01
Project end date: 2011-08-31
1T35AI065385-01A1 (2006): $62538
Transmission Dynamics Of Cryptosporidium Sp
Robert H Gilman, Professor
Johns Hopkins University W400 Wyman Park Building Baltimore, Md 212182680
Grant 5R21AI059661-02 from National Institute Of Allergy And Infectious Diseases, IRG: ECDA
Abstract: Cryptosporidium spp are protozoan parasites pathogenic to humans listed as Class B Priority pathogens. In spite of what is known about its biology, several questions concerning the dynamics of transmission and identification of infection sources have been proven difficult to investigate using microscopy 1) What is the public health significance of Cryptosporidium spp identified in animals? 2) What is the disease burden attributable to parasites of animal origin? 3) Is there a temporal or geographic clustering of Cryptosporidium spp or subtypes? Recently molecular tools have been developed to allow for the species differentiation and sub-typing of Cryptosporidium and could be used to address these questions. This project will apply molecular tools and Real-Time PCR technology to detect and type Cryptosporidium in stool specimens and household animals. Positive samples will be further sub-typed by DNA sequencing. Samples will be collected from 350 children ages 10 year or younger who are already enrolled in an on-going TMRC study where they provide weekly stool samples and epidemiological risk factor information including socioeconomic and symptoms data. This project will add a) the collection and of stool samples from all animals and family members living in the households of positive children; b) microscopy and molecular testing for Cryptosporidium spp. for all samples; c) establishment of a case-control study using two negative households for each Cryptosporidium-positive child, and d) GIS mapping of Cryptosporidium positive cases. DNA will be extracted from all microscopy-positive samples and the species of Cryptosporidium will be determined by Real-Time PCR and melting curve analysis (PCR-MCA). To determine the sub-types of Cryptosporidium and the robustness of the PCR-MCA, all isolates of C. hominis, C. parvum bovine genotype and C. meleagridis will be sequenced at the GP-60 gene locus. Data from the case-control study and GIS mapping will be analyzed for risk factor associations and geographic distribution of cases and subtypes within the community. The information generated through this project will enhance the understanding of the sources of infections the transmission of cryptosporidiosis, the distribution of Cryptosporidium genotypes in animals, sources of infection, and clustering of sub-types.
Keywords: Cryptosporidium, communicable disease transmission, cryptosporidiosis, epidemiology, geographic difference, protozoal genetics, Hispanic American, Peru, child (0-11), domestic animal, epizootiology, family, genotype, geographic site, household, information system, nucleic acid sequence, public health, zoonosis, clinical research, feces analysis, human subject, microscopy, polymerase chain reaction
Project start date: 2004-07-01
Project end date: 2007-06-30
5R21AI059661-02 (2005): $151088
1R21AI059661-01 (2004): $196632
Infectious Diseases Training Program In Peru
Robert H Gilman, Professor
International Healthjohns Hopkins University, W400 Wyman Park Building, Baltimore, Md 212182680
Grant 3D43TW006581-04S2 from Fogarty International Center, IRG: ZRG1
Project start date: 2003-09-05
Project end date: 2008-03-31
3D43TW006581-04S2 (2007): $50000
3D43TW006581-05S1 (2007): $10000
3D43TW006581-05S2 (2007): $96840
3D43TW006581-05S3 (2007): $139748
Robert H Gilman, Professor
Johns Hopkins University W400 Wyman Park Building Baltimore, Md 212182680
Grant 3D43TW001140-05S1 from Fogarty International Center, IRG: ZAI1
Project start date: 1999-07-01
Project end date: 2005-06-30
3D43TW001140-05S1 (2004): $100000
TUTORIAL IN TROPICAL HEALTH AT JHU/PERU OVERSEAS SITES
Robert H Gilman, Professor
Johns Hopkins University W400 Wyman Park Building Baltimore, Md 212182680
Grant 5T35AI007646-05 from National Institute Of Allergy And Infectious Diseases, IRG: MID
Project start date: 2000-09-15
Project end date: 2006-08-31
5T35AI007646-05 (2004): $99948
Robert H Gilman, Professor
Johns Hopkins University W400 Wyman Park Building Baltimore, Md 212182680
Grant 5D43TW001140-05 from Fogarty International Center, IRG: ZAI1
Project start date: 1999-07-01
Project end date: 2004-06-30
5D43TW001140-05 (2003): $100000
TUTORIAL IN TROPICAL HEALTH AT JHU/PERU OVERSEAS SITES
Robert H Gilman, Professor
Johns Hopkins University W400 Wyman Park Building Baltimore, Md 212182680
Grant 5T35AI007646-04 from National Institute Of Allergy And Infectious Diseases, IRG: MID
Project start date: 2000-09-15
Project end date: 2005-08-31
5T35AI007646-04 (2003): $92327
PERU EMERGING INFECTIONS TRAINING AND RESEARCH
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 5D43TW000910-05 from Fogarty International Center, IRG: ZAI1
Project start date: 1997-09-20
Project end date: 2003-12-31
5D43TW000910-05 (2001): $298096
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 5D43TW001140-03 from Fogarty International Center, IRG: ZAI1
Project start date: 1999-07-01
Project end date: 2004-06-30
5D43TW001140-03 (2001): $119958
TUTORIAL IN TROPICAL HEALTH AT JHU/PERU OVERSEAS SITES
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 5T35AI007646-02 from National Institute Of Allergy And Infectious Diseases, IRG: MID
Project start date: 2000-09-15
Project end date: 2005-08-31
5T35AI007646-02 (2001): $87059
1T35AI007646-01 (2000): $82704
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 5D43TW001140-02 from Fogarty International Center, IRG: ZAI1
Project start date: 1999-07-01
Project end date: 2004-06-30
5D43TW001140-02 (2000): $100000
PERU EMERGING INFECTIONS TRAINING AND RESEARCH
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 3D43TW000910-03S1 from Fogarty International Center, IRG: ZAI1
Project start date: 1997-09-20
Project end date: 2002-09-19
3D43TW000910-03S1 (2000): $71794
3D43TW000910-03S2 (2000): $10106
5D43TW000910-04 (2000): $193801
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 1D43TW001140-01 from Fogarty International Center, IRG: ZAI1
Project start date: 1999-07-01
Project end date: 2004-06-30
1D43TW001140-01 (1999): $53540
PERU EMERGING INFECTIONS TRAINING AND RESEARCH
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 5D43TW000910-03 from Fogarty International Center, IRG: ZAI1
Project start date: 1997-09-20
Project end date: 2002-09-19
5D43TW000910-03 (1999): $156275
5D43TW000910-02 (1998): $179723
1D43TW000910-01 (1997): $150000
SEROLOGY AS A PREDICTOR OF NEUROCYSTICERCOSIS
Robert H Gilman, Professor
International Healthjohns Hopkins University
w400 Wyman Park Building
baltimore, Md 212182680
Grant 1R03TW000598-01A1 from Fogarty International Center, IRG: ICP
Keywords: Cestoda, anthelmintic, diagnosis design /evaluation, helminthiasis, human therapy evaluation, parasitic disease chemotherapy, parasitic disease diagnosis, serology /serodiagnosis antibody formation, epilepsy clinical research, computed axial tomography, human subject, western blotting
Project start date: 1997-09-30
Project end date: 2000-07-31
1R03TW000598-01A1 (1997): $24813
Related Publications
Perilesional brain oedema and seizure activity in patients with calcified neurocysticercosis: a prospective cohort and nested case-control study. Lancet Neurol. 2008 Dec; 7( 12): 1099-1105. Epub 2008 Nov 3. PMID: 18986841 Polymerase chain reaction for chronic Trypanosoma cruzi infection yields higher sensitivity in blood clot than buffy coat or whole blood specimens. Am J Trop Med Hyg. 2008 Nov; 79( 5): 768-70. PMID: 18981520 DNA level diversity and relatedness of Helicobacter pylori strains in Peruvian shantytown families: transmission in a developing country setting. J Clin Microbiol. 2008 Oct 8. [Epub ahead of print] PMID: 18842944 Impregnated netting slows infestation by Triatoma infestans. Am J Trop Med Hyg. 2008 Oct; 79( 4): 528-34. PMID: 18840739 
Cryptosporidium species and subtypes and clinical manifestations in children, Peru. Emerg Infect Dis. 2008 Oct; 14( 10): 1567-74. PMID: 18826821 
The Infectiousness of Tuberculosis Patients Coinfected with HIV. PLoS Med. 2008 Sep 16; 5( 9): e188. [Epub ahead of print] PMID: 18798687 Synthesis, cytotoxicity, and anti-Trypanosoma cruzi activity of new chalcones. J Med Chem. 2008 Oct 9; 51( 19): 6230-4. Epub 2008 Sep 18. PMID: 18798609 Pedestrian road traffic injuries in urban Peruvian children and adolescents: case control analyses of personal and environmental risk factors. PLoS ONE. 2008 Sep 10; 3( 9): e3166. PMID: 18781206 Epidemiology of highly endemic multiply antibiotic-resistant shigellosis in children in the Peruvian Amazon. Pediatrics. 2008 Sep; 122( 3): e541-9. Epub 2008 Aug 18. Erratum in: Pediatrics. 2008 Nov;122(5):1163-4.. PMID: 18710884 Hypertension among adults in a deprived urban area of Peru - Undiagnosed and uncontrolled? BMC Res Notes. 2008 Feb 26; 1: 2. PMID: 18710540 Inter- and intra-assay reproducibility of microplate Alamar blue assay results for isoniazid, rifampicin, ethambutol, streptomycin, ciprofloxacin, and capreomycin drug susceptibility testing of Mycobacterium tuberculosis. J Clin Microbiol. 2008 Oct; 46( 10): 3526-9. Epub 2008 Aug 13. PMID: 18701659 Surveillance for early silicosis in high altitude miners using pulse oximetry. Int J Occup Environ Health. 2008 Jul-Sep; 14( 3): 187-92. PMID: 18686718 Lack of an adverse effect of Giardia intestinalis infection on the health of Peruvian children. Am J Epidemiol. 2008 Sep 15; 168( 6): 647-55. Epub 2008 Jul 31. PMID: 18669932 Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1. Am J Trop Med Hyg. 2008 Jul; 79( 1): 89-92. PMID: 18606769 Absence of brain involvement and factors related to positive serology in a prospective series of 61 cases with pulmonary hydatid disease. Am J Trop Med Hyg. 2008 Jul; 79( 1): 84-8. PMID: 18606768 Peptide YY: a gut hormone associated with anorexia during infectious diarrhea in children. J Pediatr. 2008 Nov; 153( 5): 677-82. Epub 2008 Jun 24. PMID: 18571670 Multi-country analysis of the effects of diarrhoea on childhood stunting. Int J Epidemiol. 2008 Aug; 37( 4): 816-30. Epub 2008 Jun 20. PMID: 18567626 Performance of oscillometric blood pressure devices in children in resource-poor settings. Eur J Cardiovasc Prev Rehabil. 2008 Jun; 15( 3): 362-4. PMID: 18525395 Anti-infective and cytotoxic compounds present in Blepharodon nitidum. Planta Med. 2008 Mar; 74( 4): 407-10. PMID: 18484532 Chagas disease transmission in periurban communities of Arequipa, Peru. Clin Infect Dis. 2008 Jun 15; 46( 12): 1822-8. PMID: 18462104